Description

Altretamine (Hydrochloride) CAS NO 2975-00-0 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) of significant commercial importance. Its primary value lies in its role as a precursor in the synthesis of the antineoplastic agent altretamine (hexamethylmelamine), a chemotherapeutic drug. This compound is essential for manufacturers and research institutions in the pharmaceutical and life sciences sectors requiring a reliable, high-quality building block for oncology drug development and production.

Application

• Pharmaceutical API Synthesis: Primary use as a key intermediate in the commercial production of the chemotherapeutic drug altretamine.
• Oncology Research & Development: Serves as a critical reference standard and starting material in preclinical and clinical research for developing cancer therapeutics.
• Fine Chemical Manufacturing: Utilized in the synthesis of other complex organic molecules and specialty chemicals requiring its specific triazine-based structure.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs and CDMOs engaged in the production of generic or novel oncology medications under cGMP conditions.
• Academic & Institutional Research: Used in university and government laboratories for biochemical studies related to antineoplastic mechanisms and drug metabolism.
• Analytical Reference Standard: Employed as a high-purity standard in quality control (QC) and quality assurance (QA) laboratories for HPLC, LC-MS, and other analytical methods.

Basic Information

Product Name	Altretamine (Hydrochloride)
CAS No.	2975-00-0
Molecular Formula	C9H19N6Cl
Molecular Weight	246.75 g/mol
Synonyms	Hexamethylmelamine Hydrochloride; HMM Hydrochloride; Altretamine HCl; N,N,N',N',N'',N''-Hexamethyl-1,3,5-triazine-2,4,6-triamine Hydrochloride; ENT-50852 Hydrochloride; NSC-13875
EINECS	221-009-1

Quality Control

Our Altretamine (Hydrochloride) is manufactured and tested under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets stringent specifications suitable for pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.