Description

Ethyl trans-4-Oxo-2-Butenoate is a high-purity, versatile α,β-unsaturated ester building block. This compound is valued for its reactive carbonyl and alkene functionalities, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the production of heterocyclic compounds, active pharmaceutical ingredients (APIs), and protease inhibitors.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and specialty polymers.
• Academic & Industrial R&D: Employed in method development, catalysis studies, and the synthesis of novel organic materials.
• Cross-Coupling Reactions: Acts as a substrate in Heck, Suzuki, and other palladium-catalyzed coupling reactions.
• Conjugate Addition Reactions: Utilized in Michael addition reactions to create new carbon-carbon bonds.

Basic Information

Product Name	Ethyl trans-4-Oxo-2-Butenoate
CAS No.	2960-66-9
Molecular Formula	C6H8O3
Molecular Weight	128.13 g/mol
Synonyms	trans-4-Oxo-2-butenoic acid ethyl ester; Ethyl (E)-4-oxobut-2-enoate; Ethyl 4-oxo-2-butenoate; Ethyl acetylenecarboxylate (obsolete); Ethyl 2-butenedioate, 4-oxo-; Ethyl β-formylacrylate; 2-Butenoic acid, 4-oxo-, ethyl ester, (E)-; Ethyl trans-β-formylacrylate
EINECS	220-980-5

Quality Control

Our Ethyl trans-4-Oxo-2-Butenoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.