Description

2-Chloronicotinic Acid is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a reactive chlorinated aromatic acid moiety, enabling the construction of complex molecules for high-value applications. This intermediate is essential for research and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the chloronicotinic acid scaffold contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers and photoactive compounds.
• Custom Chemical Synthesis: A fundamental building block for contract research organizations (CROs) and CDMOs producing custom intermediates for client projects.

Basic Information

Product Name	2-Chloronicotinic Acid
CAS No.	2942-59-8
Molecular Formula	C6H4ClNO2
Molecular Weight	157.55 g/mol
Synonyms	2-Chloropyridine-3-carboxylic Acid; 3-Carboxy-2-chloropyridine; 2-Chloro-3-pyridinecarboxylic Acid; Nicotinic Acid, 2-chloro-; 2-Chloro-3-carboxypyridine; 2-Cl-3-PyCOOH
EINECS	220-937-6

Quality Control

Our 2-Chloronicotinic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for use in sensitive synthetic applications. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.