Description

1-(2-Isocyanoethyl)-Pyrrolidine is a versatile isocyanide building block used in organic synthesis. Its value lies in its bifunctional nature, featuring both a reactive isocyano group and a pyrrolidine moiety, enabling its use in multicomponent reactions and as a ligand precursor. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and catalysts.

Application

• Pharmaceutical Intermediates: A key building block in the synthesis of complex molecules, including potential drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators.
• Catalyst & Ligand Development: Serves as a precursor for the creation of novel metal-organic catalysts and ligands used in asymmetric synthesis.
• Multicomponent Reactions (MCRs): Employed in Passerini and Ugi-type reactions for the efficient, one-pot construction of diverse chemical libraries.
• Material Science Research: Investigated for the synthesis of functional polymers and advanced materials with specific properties.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological systems and enzyme activity.

Basic Information

Product Name	1-(2-Isocyanoethyl)-Pyrrolidine
CAS No.	2920-10-7
Molecular Formula	C7H12N2
Molecular Weight	124.18 g/mol
Synonyms	2-(1-Pyrrolidinyl)ethyl isocyanide; 2-(Pyrrolidin-1-yl)ethyl isocyanide; 1-(2-Isocyanoethyl)pyrrolidine; 2-Isocyanoethylpyrrolidine; N-(2-Isocyanoethyl)pyrrolidine; Pyrrolidine, 1-(2-isocyanoethyl)-; Isocyanide C7H12N2
EINECS	220-873-5

Quality Control

Our 1-(2-Isocyanoethyl)-Pyrrolidine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by GC or HPLC), identity confirmation (IR, NMR), and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.