Description

3-(Trimethylsilyl)-1-propanol is a versatile organosilicon compound featuring both a reactive hydroxyl group and a hydrolytically stable trimethylsilyl moiety. This bifunctional nature makes it a valuable intermediate for introducing silicon-containing groups into organic molecules, enhancing properties like hydrophobicity, thermal stability, and surface activity. It is primarily utilized by manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for synthesis and surface modification applications.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, where the silyl group acts as a protecting group for the alcohol or modifies drug solubility and bioavailability.
• Surface Modifying Agent: Imparts hydrophobic and oleophobic properties to glass, silica, metals, and polymers, making it valuable for creating water-repellent coatings and functionalized surfaces.
• Silicone Polymer Modification: Serves as a chain extender or cross-linking agent in silicone resins and elastomers, influencing flexibility, adhesion, and compatibility with organic matrices.
• Coupling Agent in Composites: Enhances the interfacial adhesion between inorganic fillers (like glass fibers or minerals) and organic polymer matrices, improving mechanical properties in composite materials.
• Agrochemical Synthesis: Employed as a building block in the production of certain pesticides and herbicides, leveraging its ability to modify the physicochemical properties of the active ingredients.
• Lubricant and Grease Additive: Functions as a precursor for silicon-based additives that improve the thermal stability and load-bearing characteristics of synthetic lubricants.
• Adhesive and Sealant Formulations: Incorporated into formulations to improve moisture resistance, adhesion to low-energy surfaces, and long-term durability.
• Research & Development: A key reagent in organic and organometallic chemistry research for novel synthetic methodologies and material science applications.

Basic Information

Product Name	3-(Trimethylsilyl)-1-propanol
CAS No.	2917-47-7
Molecular Formula	C6H16OSi
Molecular Weight	132.28 g/mol
Synonyms	3-(Trimethylsilyl)-1-propanol; 3-(Trimethylsilyl)propan-1-ol; 1-Hydroxy-3-(trimethylsilyl)propane; (3-Hydroxypropyl)trimethylsilane; Trimethyl(3-hydroxypropyl)silane; TMS-propanol; γ-(Trimethylsilyl)propyl alcohol
EINECS	220-848-7

Quality Control

Our 3-(Trimethylsilyl)-1-propanol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for demanding synthesis applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, containers must be kept tightly sealed to prevent moisture absorption, which can lead to decomposition. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.428 - 1.432
Density (20°C)	0.84 - 0.88 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.