Description

Cyanomethyl 2-Phenylmethoxycarbonylaminoacetate is a versatile and high-purity chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a protected glycine derivative, enabling the controlled introduction of amino acid functionalities into complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of peptides, peptidomimetics, and other bioactive molecules requiring specific stereochemical and functional group control.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid derivative to construct specific peptide sequences.
• Agrochemical Research: Serves as an intermediate in the development of new herbicides, fungicides, and insecticides with peptide-like structures.
• Bioconjugation Chemistry: Employed in the preparation of linkers and reagents for bioconjugation, useful in antibody-drug conjugates (ADCs) and diagnostic probes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Cyanomethyl 2-Phenylmethoxycarbonylaminoacetate
CAS No.	2899-56-1
Molecular Formula	C12H12N2O4
Molecular Weight	248.24 g/mol
Synonyms	N-Carbobenzoxyglycine cyanomethyl ester; Cbz-Gly-OCM; Z-Glycine cyanomethyl ester; (Benzyloxycarbonyl)glycine cyanomethyl ester; Glycine, N-[(phenylmethoxy)carbonyl]-, cyanomethyl ester; N-(Benzyloxycarbonyl)glycine cyanomethyl ester; 2-[[(Benzyloxy)carbonyl]amino]acetic acid cyanomethyl ester; Z-Gly-OCM
EINECS	220-793-9

Quality Control

Our Cyanomethyl 2-Phenylmethoxycarbonylaminoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with the expectations of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed when not in use to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.