Description

Tms Dl-Alanine CAS NO 2899-44-7 is a protected derivative of the amino acid alanine, where the amine and carboxylic acid functional groups are modified with trimethylsilyl (Tms) groups. This chemical modification is crucial for enhancing stability and solubility in organic synthesis, particularly in peptide and complex molecule construction. It serves as a vital building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors, where precise molecular assembly is required.

Application

• Pharmaceutical Intermediate: A key protected amino acid synthon for the synthesis of peptide-based drugs, APIs (Active Pharmaceutical Ingredients), and novel therapeutic compounds.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions during the coupling of amino acid sequences.
• Agrochemical Research: Employed in the development and research of new pesticides, herbicides, and plant growth regulators that incorporate amino acid motifs.
• Bioconjugation & Labeling: Acts as a precursor for creating modified amino acids used in bioconjugation chemistry for drug delivery systems or diagnostic agents.
• Material Science: Utilized in the research of bio-inspired polymers and materials where amino acid derivatives provide specific structural or functional properties.
• Chemical Biology Probes: Serves as a starting material for synthesizing probes and tools used to study biological processes and enzyme mechanisms.

Basic Information

Product Name	Tms Dl-Alanine
CAS No.	2899-44-7
Molecular Formula	C9H23NO2Si2
Molecular Weight	233.46 g/mol
Synonyms	N,O-Bis(trimethylsilyl)-DL-alanine; DL-Alanine, N,O-bis(trimethylsilyl)-; Alanine, N,O-bis(trimethylsilyl)-, DL-; Bis(trimethylsilyl) alanine; TMS-Alanine; TMS-DL-Ala; (RS)-2-[(Trimethylsilyl)amino]-3-(trimethylsilyloxy)propanoic acid
EINECS	Contact for details

Quality Control

Our Tms Dl-Alanine is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and synthesis applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For specific project requirements, custom purity grades and analytical documentation can be discussed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.