Description

Rac-(R*)-2-Isobutylglycine Ethyl Ester is a high-purity, non-natural amino acid derivative used as a critical chiral building block in advanced organic synthesis. This compound is essential for the development of novel pharmaceuticals and bioactive molecules, offering a versatile scaffold for peptidomimetics and enzyme inhibitors. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly peptidomimetics and enzyme inhibitors.
• Medicinal Chemistry Research: Used as a building block for constructing novel molecular libraries and exploring structure-activity relationships (SAR) in drug discovery.
• Peptide Synthesis: Serves as a protected amino acid derivative for the solid-phase or solution-phase synthesis of modified peptides and peptide analogs.
• Chemical Biology Probes: Incorporated into molecules designed to study biological pathways and protein functions.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex target molecules in pilot plant and manufacturing settings.
• Academic Research: Used in university and institutional labs for methodological development in asymmetric synthesis and organocatalysis.

Basic Information

Item	Details
Product Name	Rac-(R*)-2-Isobutylglycine Ethyl Ester
CAS No.	2899-43-6
Molecular Formula	C9H19NO2
Molecular Weight	173.25 g/mol
Synonyms	Ethyl 2-Amino-4-methylpentanoate; DL-2-Amino-4-methylpentanoic Acid Ethyl Ester; (±)-2-Amino-4-methylvaleric Acid Ethyl Ester; Ethyl DL-Leucinate; Ethyl 2-Aminoisocaproate; Ethyl (±)-2-Amino-4-methylvalerate; 2-Isobutylglycine Ethyl Ester; Ethyl 2-Amino-4-methylpentanoate
EINECS	220-795-6

Quality Control

Our Rac-(R*)-2-Isobutylglycine Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric purity, and impurity profiles. We support our clients' regulatory needs with documentation suitable for research and development filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Raccemic mixture
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.