Description

L-Aspartic Acid Dibenzyl Ester 4-Toluenesulfonate is a key protected amino acid derivative, specifically the dibenzyl ester tosylate salt of L-aspartic acid. This compound is critically important as a high-purity synthetic building block and chiral intermediate in advanced organic synthesis. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions for the production of peptides, peptidomimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for peptide-based drugs and enzyme inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) where the dibenzyl ester protecting groups offer orthogonal deprotection strategies.
• Biochemical Research: Employed in the study of enzyme mechanisms, receptor-ligand interactions, and the development of novel diagnostic agents.
• Asymmetric Synthesis: Acts as a chiral pool starting material or auxiliary for the construction of complex molecules with defined stereochemistry.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances that require aspartic acid-derived structures.
• Academic & Process Development: A valuable reagent for method development, scale-up studies, and teaching advanced synthetic organic chemistry techniques.

Basic Information

Product Name	L-Aspartic Acid Dibenzyl Ester 4-Toluenesulfonate
CAS No.	2886-33-1
Molecular Formula	C25H27NO7S
Molecular Weight	485.55 g/mol
Synonyms	L-Aspartic Acid α,β-Dibenzyl Ester p-Toluenesulfonate Salt; H-Asp(OBzl)-OBzl•TosOH; Dibenzyl L-aspartate tosylate; (S)-2,4-Bis(benzyloxy)-4-oxobutanoic acid 4-methylbenzenesulfonate; L-Aspartic acid dibenzyl ester tosylate salt; Aspartic acid, dibenzyl ester, L-, 4-methylbenzenesulfonate; Benzyl L-aspartate benzyl p-toluenesulfonate; DBAT
EINECS	Contact for details

Quality Control

Our L-Aspartic Acid Dibenzyl Ester 4-Toluenesulfonate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity, chiral integrity, and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and related substances are provided and available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.