Description

L-Phenylalanine Butyl Ester is a chiral amino acid ester derivative, serving as a crucial protected intermediate in advanced organic synthesis. Its primary value lies in providing a versatile building block for the construction of complex peptides, pharmaceuticals, and fine chemicals, where the butyl ester group offers specific reactivity and solubility advantages. This high-purity intermediate is essential for research institutions and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of peptide-based drugs, enzyme inhibitors, and other bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide chemistry as a protected amino acid derivative.
• Bioconjugation & Prodrug Development: Facilitates the attachment of phenylalanine moieties to larger molecules or the creation of ester-based prodrugs.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to induce chirality.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Biochemical Research: Utilized in metabolic studies, enzyme substrate preparation, and as a standard in analytical method development.

Basic Information

Product Name	L-Phenylalanine Butyl Ester
CAS No.	2885-10-1
Molecular Formula	C₁₃H₁₉NO₂
Molecular Weight	221.30 g/mol
Synonyms	(S)-2-Amino-3-phenylpropanoic acid butyl ester; L-Phenylalanine n-butyl ester; Butyl L-phenylalaninate; (S)-2-Amino-3-phenylpropionic acid butyl ester; Phenylalanine butyl ester; H-Phe-OBu; Fmoc-Phe-OtBu (protected form derivative); L-α-Amino-β-phenylpropionic acid butyl ester
EINECS	220-760-5

Quality Control

Our L-Phenylalanine Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.