Description

3-(4-Chloro-Phenyl)-3-Oxo-Propionic Acid Ethyl Ester is a versatile and high-purity organic building block, essential for advanced chemical synthesis. Its value lies in its role as a key intermediate for creating complex molecules with high specificity and yield. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the production of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with aryl ketone or β-keto ester backbones.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and insecticides, leveraging the reactive 4-chlorophenyl and β-keto ester functional groups.
• Organic Synthesis Building Block: Serves as a versatile reagent for Claisen condensations, Michael additions, and cyclization reactions to construct heterocyclic compounds.
• Material Science Research: Employed in the development of organic ligands, monomers for polymers, and advanced organic electronic materials.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex organic dyes and pigments due to its aromatic structure.

Basic Information

Product Name	3-(4-Chloro-Phenyl)-3-Oxo-Propionic Acid Ethyl Ester
CAS No.	2881-63-2
Molecular Formula	C11H11ClO3
Molecular Weight	226.66 g/mol
Synonyms	Ethyl 3-(4-Chlorophenyl)-3-oxopropanoate; Ethyl 4-Chlorobenzoylacetate; 4'-Chlorobenzoylacetic Acid Ethyl Ester; 3-Oxo-3-(4-chlorophenyl)propionic Acid Ethyl Ester; 4-Chlorobenzoylacetic Acid Ethyl Ester; Ethyl (4-Chlorobenzoyl)acetate; 2881-63-2; NSC 404087
EINECS	220-754-5

Quality Control

Our 3-(4-Chloro-Phenyl)-3-Oxo-Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.