Description

(E)-1-(2-Hydroxyphenyl)-3-(2-Thienyl)-2-Propen-1-One is a high-purity chalcone derivative, a versatile organic building block prized for its unique molecular architecture combining phenolic and thienyl moieties. This compound is critical for advanced research and development, particularly in the synthesis of novel materials and active pharmaceutical ingredients (APIs) with tailored optical and biological properties. It serves as a key intermediate for scientists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting anti-inflammatory, antimicrobial, or anticancer pathways.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a core structure for developing advanced organic semiconductors and emissive materials due to its conjugated system.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its bioactive chalcone scaffold.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex heterocyclic compounds and fine chemicals.
• UV Absorber & Stabilizer Precursor: Acts as a starting material for synthesizing compounds used in polymer stabilization and sunscreen formulations.
• Fluorescent Probe Development: Utilized in research to create sensitive fluorescent markers and sensors for biological or chemical detection.

Basic Information

Product Name	(E)-1-(2-Hydroxyphenyl)-3-(2-Thienyl)-2-Propen-1-One
CAS No.	2875-22-1
Molecular Formula	C13H10O2S
Molecular Weight	230.28 g/mol
Synonyms	2'-Hydroxychalcone; 2'-Hydroxy-2-thienylchalcone; (E)-1-(2-Hydroxyphenyl)-3-(thiophen-2-yl)prop-2-en-1-one; 3-(2-Thienyl)-1-(2-hydroxyphenyl)-2-propen-1-one; 2'-Hydroxy-3-(2-thienyl)propenophenone; 2'-Hydroxy-2-thienylchalcone; 1-(2-Hydroxyphenyl)-3-(2-thienyl)-2-propen-1-one
EINECS	Contact for details

Quality Control

Our (E)-1-(2-Hydroxyphenyl)-3-(2-Thienyl)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	142 - 148 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.