Description

Atropine Methyl Bromide is a quaternary ammonium salt derivative of the tropane alkaloid atropine. This compound is valued for its potent anticholinergic activity and is a key intermediate in the synthesis of specialized pharmaceuticals and research chemicals. It is primarily utilized by the pharmaceutical industry, contract research organizations (CROs), and academic institutions engaged in neuropharmacology and medicinal chemistry research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of anticholinergic and antispasmodic drugs.
• Research Chemical: Used in pharmacological studies to investigate muscarinic acetylcholine receptor (mAChR) antagonism and autonomic nervous system function.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Chemical Synthesis: Employed in organic synthesis to introduce the tropane moiety or quaternary ammonium functionality into more complex molecules.

Basic Information

Product Name	Atropine Methyl Bromide
CAS No.	2870-71-5
Molecular Formula	C18H26BrNO3
Molecular Weight	384.31 g/mol
Synonyms	Methylatropine Bromide; Atropine Methobromide; (8-Methyl-8-azabicyclo[3.2.1]oct-3-yl) 3-hydroxy-2-phenylpropanoate methobromide; Tropine tropate methyl bromide; DL-Hyoscyamine methyl bromide; Scopolamine methyl bromide (related compound); Atropine N-Methyl Bromide; Atropine Methobromide Salt
EINECS	220-704-9

Quality Control

Our Atropine Methyl Bromide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. The product can be supplied to meet various pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.