Description

16α-Methyl-17-Hydroxyprogesterone is a synthetic steroid derivative of progesterone, known for its potent progestogenic activity. This compound serves as a critical pharmaceutical intermediate in the synthesis of high-value therapeutic agents. It is primarily required by manufacturers in the pharmaceutical and life sciences sectors for research and development, as well as for the production of specialized steroid-based medications.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the multi-step synthesis of advanced steroid-based drugs.
• Progestogen Research: Used in biochemical and pharmacological research to study progestogen receptor activity and hormone mechanisms.
• Reference Standard: Serves as a high-purity analytical reference standard for quality control and method development in pharmaceutical laboratories.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the manufacturing process of specific therapeutic progestins.
• Endocrinology Studies: Utilized in preclinical and clinical research models to investigate hormonal pathways and effects.

Basic Information

Product Name	16α-Methyl-17-Hydroxyprogesterone
CAS No.	2868-02-2
Molecular Formula	C22H32O3
Molecular Weight	344.49 g/mol
Synonyms	16α-Methyl-17α-hydroxyprogesterone; 16α-Methyl-17α-OH-P; 16α-Methyl-17α-hydroxy-4-pregnene-3,20-dione; 16α-Methyl-17α-hydroxy-δ4-pregnene-3,20-dione; 16α-Methyl-17α-hydroxyprogesterone; 16α-Methyl-17α-OH-P4; Medroxyprogesterone Acetate Intermediate
EINECS	220-698-5

Quality Control

Our 16α-Methyl-17-Hydroxyprogesterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR), to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.