Description

Benzeneacetic Acid, .Alpha.-Bromo-2-Chloro-, Ethyl Ester is a high-purity halogenated aromatic ester building block, valued for its reactive bromine and chlorine substituents which enable selective synthetic transformations. This compound is essential for advanced organic synthesis, particularly in the construction of complex pharmaceutical intermediates and agrochemical active ingredients. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated phenylacetic acid derivatives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Serves as a versatile electrophile in nucleophilic substitution reactions and palladium-catalyzed cross-coupling reactions.
• Ligand and Catalyst Precursor: Employed in the development of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or functionalizing agent for specialty polymers and advanced organic materials.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific halogenation patterns.

Basic Information

Product Name	Benzeneacetic Acid, .Alpha.-Bromo-2-Chloro-, Ethyl Ester
CAS No.	2856-79-3
Molecular Formula	C10H10BrClO2
Molecular Weight	277.54 g/mol
Synonyms	Ethyl 2-Bromo-2-(2-chlorophenyl)acetate; 2-Bromo-2-(2-chlorophenyl)acetic Acid Ethyl Ester; α-Bromo-o-chlorophenylacetic Acid Ethyl Ester; Ethyl α-Bromo-2-chlorobenzeneacetate; NSC 3349; (2-Chlorophenyl)(bromo)acetic Acid Ethyl Ester; Ethyl (2-Bromo-2-(2-chlorophenyl)acetate)
EINECS	220-667-4

Quality Control

Our Benzeneacetic Acid, .Alpha.-Bromo-2-Chloro-, Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.