Description

2,6-Dimethylphenyl Isocyanide is a versatile aromatic isocyanide building block, essential for the synthesis of complex heterocycles and metal-organic frameworks. Its value lies in its role as a key ligand in organometallic chemistry and a precursor in multicomponent reactions, enabling the efficient construction of pharmaceuticals and advanced materials. This high-purity intermediate is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing heterocyclic compounds and potential active pharmaceutical ingredients (APIs).
• Organometallic Catalyst Ligand: Used as a ligand in transition metal catalysis for cross-coupling and other synthetic transformations.
• Material Science Research: Employed in the construction of metal-organic frameworks (MOFs) and coordination polymers with tailored properties.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Multicomponent Reactions (MCRs): A key reactant in Passerini and Ugi-type reactions for rapid library synthesis in drug discovery.
• Chemical Research & Development: Fundamental reagent for methodological development in organic and inorganic synthesis laboratories.

Basic Information

Product Name	2,6-Dimethylphenyl Isocyanide
CAS No.	2769-71-3
Molecular Formula	C9H9N
Molecular Weight	131.18 g/mol
Synonyms	2,6-Dimethylphenyl isocyanide; 2,6-Dimethylbenzenecarbonitrile; 2,6-Xylyl isocyanide; 2,6-Dimethylphenylisonitrile; Isocyano-2,6-dimethylbenzene; 1-Isocyano-2,6-dimethylbenzene; 2,6-Dimethylphenyl isonitrile; (2,6-Dimethylphenyl)isocyanide
EINECS	220-447-3

Quality Control

Our 2,6-Dimethylphenyl Isocyanide is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC and HPLC analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its properties of being easily oxidized and highly volatile, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to minimize decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.