Description

n-Butylisocyanide is a versatile organic building block and ligand, primarily valued for its role as a key precursor in organometallic chemistry and heterocyclic synthesis. Its isocyanide functional group makes it a critical reagent for multicomponent reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for research and development in the pharmaceutical, agrochemical, and material science industries, where it is used to create novel compounds and catalysts.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Catalyst Ligand: Used in transition metal catalysis, particularly in palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Employed in the research and production of novel pesticides and herbicides.
• Material Science: Serves as a monomer or modifier in the development of specialized polymers and functional materials.
• Multicomponent Reactions (MCRs): A crucial component in Passerini and Ugi reactions for the rapid generation of chemical diversity libraries.
• Chemical Research: Used in academic and industrial R&D for methodological development and novel compound discovery.

Basic Information

Product Name	n-Butylisocyanide
CAS No.	2769-64-4
Molecular Formula	C5H9N
Molecular Weight	83.13 g/mol
Synonyms	Butyl isocyanide; 1-Isocyanobutane; Isocyanobutane; Butylisonitrile; n-Butyl isonitrile; Pentanenitrile, isocyano-; NSC 60539
EINECS	220-450-5

Quality Control

Our n-Butylisocyanide is produced and tested under stringent quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to meet the rigorous demands of research and industrial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area, away from heat and ignition sources. Due to its highly volatile and easily oxidized nature, containers must be kept tightly sealed and handled with appropriate precautions to minimize exposure to air and moisture. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.