Description

17-Hydroxy-1A,2A-Methylenepregna-4,6-Diene-3,20-Dione Acetate is a high-purity synthetic steroid intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of more complex steroidal drugs, offering a versatile scaffold for chemical modification. It is primarily sought by pharmaceutical manufacturers and advanced research institutions engaged in the development of novel therapeutic agents, particularly within the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Hormone Analog Synthesis: Serves as a starting material for the development of modified steroid hormones with targeted biological activity.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Utilized in studies investigating steroid receptor interactions and metabolic pathways.

Basic Information

Product Name	17-Hydroxy-1A,2A-Methylenepregna-4,6-Diene-3,20-Dione Acetate
CAS No.	2701-50-0
Molecular Formula	C₂₄H₃₀O₅
Molecular Weight	398.50 g/mol
Synonyms	1α,2α-Methylene-17α-hydroxy-6-dehydroprogesterone acetate; 17α-Hydroxy-1α,2α-methylenepregna-4,6-diene-3,20-dione acetate; 1,2α-Methylene-6-dehydro-17α-hydroxyprogesterone acetate; 6-Dehydro-1,2α-methyleneprogesterone-17α-ol acetate; NSC 121773; 1,2α-Methylene-6-dehydro-17α-acetoxyprogesterone
EINECS	Contact for details

Quality Control

Our 17-Hydroxy-1A,2A-Methylenepregna-4,6-Diene-3,20-Dione Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.