Description

2,8-Diazaspiro[4.5]Decane-1,3-Dione, (Hydrochloride) (1:1) is a high-purity, nitrogen-containing spirocyclic compound with the CAS number 2696-03-9. This specialized heterocyclic building block is valued for its unique structural framework, which is critical for imparting specific biological and physicochemical properties in advanced molecular design. It serves as a key synthetic intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients.

Application

This versatile spirocyclic intermediate is primarily employed in sophisticated organic synthesis. Its applications include:

• Pharmaceutical Intermediate: A crucial building block for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its complex heterocyclic structure.
• Chemical Research & Development: Serves as a scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Precursor: Potential use in synthesizing specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Advanced Material Science: Exploration into functional materials due to its rigid, three-dimensional spiro structure.

Basic Information

Product Name	2,8-Diazaspiro[4.5]Decane-1,3-Dione, (Hydrochloride) (1:1)
CAS No.	2696-03-9
Molecular Formula	C8H12N2O2 • HCl
Molecular Weight	204.65 g/mol (Free base: 168.19 g/mol)
Synonyms	1,3-Diazaspiro[4.5]decane-2,4-dione hydrochloride; 2,8-Diazaspiro[4.5]decane-1,3-dione hydrochloride; Spiro[4.5]decane-1,3-dione, 2,8-diaza-, hydrochloride; 1,3-Diazaspiro[4.5]decane-2,4-dione, monohydrochloride; 2,4-Dioxo-1,3-diazaspiro[4.5]decane hydrochloride; 2,8-Diazaspiro[4.5]decan-1,3-dione hydrochloride
EINECS	Contact for details

Quality Control

Our 2,8-Diazaspiro[4.5]Decane-1,3-Dione Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters including assay (HPLC), impurity profile, and residual solvent content, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere or in a desiccator after opening to prevent moisture uptake. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.