Description

Bromonordiazepam CAS NO 2694-61-3 is a benzodiazepine derivative of significant interest in pharmaceutical research and development. This compound serves as a crucial intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and reference standards. It is primarily utilized by research institutions, pharmaceutical manufacturers, and analytical laboratories engaged in neuropharmacology and medicinal chemistry. Its well-defined structure makes it a valuable building block for exploring new therapeutic pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of advanced benzodiazepine-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in laboratories.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies aimed at developing new central nervous system (CNS) agents.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for related pharmaceutical compounds.
• Analytical Testing: Used as an impurity standard in HPLC and LC-MS methods to ensure the purity and safety of final drug products.

Basic Information

Product Name	Bromonordiazepam
CAS No.	2694-61-3
Molecular Formula	C₁₅H₁₀BrN₃O
Molecular Weight	328.16 g/mol
Synonyms	7-Bromo-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Bromo-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one; 7-Bromonordiazepam; Desmethyldiazepam 7-bromo derivative; Ro 05-2921; Bromodesmethyldiazepam; 7-Br-nordiazepam
EINECS	Contact for details

Quality Control

Our Bromonordiazepam is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and control of related substances and residual solvents. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.