Description

Propanedioic Acid,2,2-Di-2-Propyn-1-Yl-, 1,3-Diethyl Ester is a specialized diester derivative of propanedioic acid (malonic acid) featuring propargyl (2-propynyl) substituents. This compound is valued as a versatile chemical intermediate and building block in advanced organic synthesis, particularly for introducing functionalized moieties into target molecules. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially those requiring propargyl or malonate-based frameworks.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its specific structure imparts desired biological activity.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, including polyesters and resins with tailored thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex organic molecules via reactions such as Michael additions, alkylations, and cyclizations.
• Material Science Research: Investigated for use in developing advanced materials, including metal-organic frameworks (MOFs) or functional coatings.
• Chemical Derivatization: Utilized to modify surfaces or other molecules by introducing propargyl groups for subsequent "click chemistry" reactions like the copper-catalyzed azide-alkyne cycloaddition (CuAAC).

Basic Information

Product Name	Propanedioic Acid,2,2-Di-2-Propyn-1-Yl-, 1,3-Diethyl Ester
CAS No.	2689-88-5
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	Diethyl 2,2-bis(prop-2-yn-1-yl)malonate; Diethyl 2,2-Dipropargylmalonate; 2,2-Bis(2-Propynyl)malonic Acid Diethyl Ester; Malonic Acid, 2,2-Bis(2-propynyl)-, Diethyl Ester; Diethyl Dipropargylmalonate; 1,3-Diethyl 2,2-Dipropargylmalonate; 2,2-Dipropargylmalonic Acid Diethyl Ester; Propanedioic Acid, 2,2-Bis(2-propynyl)-, 1,3-Diethyl Ester
EINECS	Contact for details

Quality Control

Our production of Propanedioic Acid,2,2-Di-2-Propyn-1-Yl-, 1,3-Diethyl Ester (CAS 2689-88-5) adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific research or industrial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.