Description

Diethyl (3-Pyridinylmethyl)Phosphonate is a versatile organophosphorus compound that serves as a critical building block in advanced organic synthesis. Its primary value lies in its role as a key reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient construction of complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing vinylpyridine or other unsaturated heterocyclic motifs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its phosphonate group facilitates the creation of specific bioactive structures.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized phosphine-based ligands used in homogeneous catalysis.
• Material Science Research: Employed in the development of functional organic materials, including metal-organic frameworks (MOFs) and polymers with tailored properties.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic chemistry and for constructing complex molecular architectures in research settings.

Basic Information

Product Name	Diethyl (3-Pyridinylmethyl)Phosphonate
CAS No.	2682-86-2
Molecular Formula	C10H16NO3P
Molecular Weight	229.21 g/mol
Synonyms	Diethyl (pyridin-3-ylmethyl)phosphonate; (3-Pyridylmethyl)phosphonic Acid Diethyl Ester; Diethyl 3-Pyridylmethylphosphonate; Phosphonic Acid, P-[(3-Pyridinyl)methyl]-, Diethyl Ester; Diethyl (3-Pyridylmethyl)phosphonate; NSC 163063
EINECS	Contact for details

Quality Control

Our Diethyl (3-Pyridinylmethyl)Phosphonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) detailing all relevant specifications are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.