Description

α-D-Glucopyranoside, Methyl 2,3,4,6-Tetrakis-o-(Trimethylsilyl)- is a fully protected carbohydrate derivative where all hydroxyl groups are shielded by trimethylsilyl (TMS) ether groups. This compound is a critical synthetic intermediate, valued for its role in complex organic synthesis where selective deprotection strategies are required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of glycosylated compounds, nucleosides, and other bioactive molecules.

Application

• Glycosylation Reagent: Serves as a key building block in the stereoselective synthesis of complex oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediate: Used in the research and production of antiviral drugs, antibiotics, and other therapeutics that contain sugar moieties.
• Carbohydrate Chemistry Research: Essential for academic and industrial R&D focused on developing new synthetic methodologies for protected sugars.
• Agrochemical Synthesis: Employed in creating novel glycosylated pesticides or plant growth regulators.
• Chiral Pool Starting Material: Provides a readily available, enantiomerically pure scaffold for the synthesis of other chiral, non-racemic compounds.
• Protecting Group Strategy: The TMS groups allow for sequential and selective deprotection, enabling precise control over synthetic pathways.

Basic Information

Product Name	α-D-Glucopyranoside, Methyl 2,3,4,6-Tetrakis-o-(Trimethylsilyl)-
CAS No.	2641-79-4
Molecular Formula	C19H46O6Si4
Molecular Weight	482.92 g/mol
Synonyms	Methyl 2,3,4,6-Tetra-O-trimethylsilyl-α-D-glucopyranoside; Methyl α-D-Glucopyranoside 2,3,4,6-Tetrakis(trimethylsilyl) Ether; α-D-Glucopyranoside, methyl, 2,3,4,6-tetrakis-O-(trimethylsilyl)-; Methyl α-D-glucoside per-O-trimethylsilyl ether; TMS-protected methyl α-D-glucoside; Methyl O-trimethylsilyl-α-D-glucopyranoside; 1-O-Methyl-2,3,4,6-tetra-O-trimethylsilyl-α-D-glucopyranose
EINECS	Contact for details

Quality Control

Our α-D-Glucopyranoside, Methyl 2,3,4,6-Tetrakis-o-(Trimethylsilyl)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent hydrolysis of the silyl ether protecting groups.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.