Description

5-(Azidomethyl)Benzo[D][1,3]Dioxole Hydrochloride is a versatile and reactive organic salt, primarily valued as a key synthetic intermediate in advanced organic chemistry. Its structure, featuring both an azide functional group and a benzodioxole moiety, makes it a crucial building block for the synthesis of complex heterocyclic compounds and pharmaceuticals. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for click chemistry, bioconjugation, and novel drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and metabolic disorders.
• Click Chemistry Reagent: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for the efficient and modular construction of complex molecular architectures.
• Bioconjugation Linker: Enables the site-specific labeling and functionalization of biomolecules such as proteins, peptides, and oligonucleotides for diagnostic and therapeutic applications.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Used in the development of functional polymers, dendrimers, and smart materials where the azide group facilitates cross-linking and property modification.
• Chemical Biology Probes: Integral to the creation of activity-based probes for studying enzyme function and metabolic pathways within living systems.

Basic Information

Item	Details
Product Name	5-(Azidomethyl)Benzo[D][1,3]Dioxole Hydrochloride
CAS No.	2620-49-7
Molecular Formula	C9H8N3O2·HCl
Molecular Weight	231.64 g/mol
Synonyms	5-(Azidomethyl)-1,3-benzodioxole Hydrochloride; 1,3-Benzodioxole, 5-(azidomethyl)-, hydrochloride; Piperonyl Azide Hydrochloride; Azidomethylenedioxybenzene Hydrochloride; NSC 403714 Hydrochloride; 5-Azidomethyl-1,3-benzodioxole HCl
EINECS	Contact for details

Quality Control

Our 5-(Azidomethyl)Benzo[D][1,3]Dioxole Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent chemical identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere when appropriate. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.