Description

Diethyl(4-Nitrobenzyl)Phosphonate is a versatile organophosphorus compound characterized by its phosphonate ester and nitrobenzyl functional groups. This chemical serves as a critical synthetic intermediate, enabling the construction of complex molecules through reactions like the Horner-Wadsworth-Emmons olefination. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require high-purity building blocks for drug discovery and active ingredient synthesis. Its unique structure facilitates the introduction of nitrobenzyl-protected functionalities and carbon-carbon double bonds into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring nitrobenzyl or vinylbenzyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its phosphonate group is valuable for creating specific bioactive structures.
• Organic Synthesis & Research: Employed as a specialized reagent in academic and industrial R&D laboratories for constructing complex organic molecules, especially via olefination reactions to form alkenes.
• Material Science Precursor: Acts as a monomer or modifying agent in the development of specialty polymers and functional materials.
• Ligand and Catalyst Development: Useful in the preparation of phosphonate-based ligands for metal catalysis and coordination chemistry.

Basic Information

Product Name	Diethyl(4-Nitrobenzyl)Phosphonate
CAS No.	2609-49-6
Molecular Formula	C11H16NO5P
Molecular Weight	273.22 g/mol
Synonyms	Diethyl (4-Nitrobenzyl)phosphonate; (4-Nitrobenzyl)phosphonic Acid Diethyl Ester; Diethyl P-(4-Nitrobenzyl)phosphonate; Phosphonic Acid, P-[(4-Nitrophenyl)methyl]-, Diethyl Ester; Diethyl 4-Nitrobenzylphosphonate; (4-Nitrobenzyl)diethyl Phosphonate; NSC 404083; EINECS 220-024-5
EINECS	220-024-5

Quality Control

Our Diethyl(4-Nitrobenzyl)Phosphonate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports applications requiring high-purity intermediates, from research to commercial-scale production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.