Description

α,α-Bis(Hydroxymethyl)Benzeneacetic Acid (1R,5S)-8-Methyl-8-Azabicyclo[3.2.1]Oct-3α-Yl Ester is a specialized pharmaceutical intermediate with a complex bicyclic structure. This compound is of significant value for its role in the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and high-value specialty products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production route for specific APIs, leveraging its unique ester and tropane-related structure.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides with specific biological activity.
• Fine Chemical Production: Employed in the manufacture of high-purity, complex organic compounds for research and industrial applications.
• Biochemical Research: Utilized as a reference standard or synthetic target in pharmacological and biochemical studies.
• Process Chemistry Development: Acts as a critical intermediate for scaling up synthetic routes in process optimization.

Basic Information

Product Name	α,α-Bis(Hydroxymethyl)Benzeneacetic Acid (1R,5S)-8-Methyl-8-Azabicyclo[3.2.1]Oct-3α-Yl Ester
CAS No.	2515-36-8
Molecular Formula	C19H25NO5
Molecular Weight	347.41 g/mol
Synonyms	Benzeneacetic acid, α,α-bis(hydroxymethyl)-, (1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3α-yl ester; Tropine α,α-bis(hydroxymethyl)phenylacetate; 3α-Tropanyl α,α-bis(hydroxymethyl)phenylacetate; (3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl α,α-bis(hydroxymethyl)benzeneacetate; Phenylacetic acid, α,α-bis(hydroxymethyl)-, 3α-tropanyl ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our α,α-Bis(Hydroxymethyl)Benzeneacetic Acid (1R,5S)-8-Methyl-8-Azabicyclo[3.2.1]Oct-3α-Yl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed specifications from methods including HPLC, NMR, and IR are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.