Description

17α-(Acetyloxy)-6,16α-Dimethylpregna-4,6-Diene-3,20-Dione is a high-purity synthetic steroid intermediate of significant commercial and research interest. This compound is valued for its role as a critical building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of steroidal drugs and reference standards. Consistent quality and reliable supply are paramount for its successful application in advanced synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of steroidal drugs, including certain corticosteroids and progestogens.
• Research & Development: Used in academic and industrial laboratories for investigating novel steroid synthesis routes and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in the production of specialized steroid derivatives for biochemical and pharmacological studies.

Basic Information

Item	Details
Product Name	17α-(Acetyloxy)-6,16α-Dimethylpregna-4,6-Diene-3,20-Dione
CAS No.	2497-80-5
Molecular Formula	C25H32O4
Molecular Weight	396.52 g/mol
Synonyms	6,16α-Dimethylpregna-4,6-diene-3,20-dione 17-acetate; 17α-Acetoxy-6,16α-dimethylpregna-4,6-diene-3,20-dione; 6,16α-Dimethyl-17α-acetoxypregna-4,6-diene-3,20-dione; 6,16α-Dimethyl-δ4,6-pregnadiene-3,20-dione-17α-ol acetate; Steroid Intermediate 2497-80-5; 6,16α-Dimethyl-17α-acetoxyprogesterone (derivative)
EINECS	Contact for details

Quality Control

Our 17α-(Acetyloxy)-6,16α-Dimethylpregna-4,6-Diene-3,20-Dione is produced under strict quality management protocols. The product undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the exacting standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each batch to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.