Description

5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinoline,6,7,7A,8-Tetrahydro-11,12-Dimethoxy-7-Methyl-, (S)- (9Ci) is a high-purity, chiral alkaloid derivative of significant interest in advanced organic synthesis. This compound serves as a critical key intermediate or reference standard for the research and development of novel pharmaceutical agents and bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential therapeutic agents, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control, method development, and identification in related chemical processes.
• Asymmetric Synthesis: Utilized in the development of novel catalytic or stoichiometric asymmetric reactions due to its defined stereochemistry.
• Biochemical Research: Investigated for its interaction with biological receptors or enzymes as part of pharmacological profiling.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinoline,6,7,7A,8-Tetrahydro-11,12-Dimethoxy-7-Methyl-, (S)- (9Ci)
CAS No.	2490-83-7
Molecular Formula	C20H21NO4
Molecular Weight	339.39 g/mol
Synonyms	(S)-7-Methyl-6,7,7a,8-tetrahydro-11,12-dimethoxybenzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline; (S)-Thalictricine; (S)-Thalictricine methyl ether; Thalictricine, (S)-; 1,3-Benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-11,12-dimethoxy-7-methyl-, (S)-; Berbine, 9,10-dimethoxy-2,3-(methylenedioxy)-13-methyl-, (S)-; (S)-11,12-Dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline
EINECS	Contact for details

Quality Control

Our production of this specialty chemical adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (S-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.