Description

Boc-Met-Onp is a specialized amino acid derivative used as a key building block in peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity intermediates to ensure the integrity of complex peptide chains. It is primarily utilized in pharmaceutical R&D, biotechnology, and fine chemical synthesis for the production of therapeutic peptides and novel biomolecules. Its reliable performance makes it essential for applications demanding precise molecular assembly.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a protected methionine derivative for the controlled elongation of peptide sequences.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for constructing specific peptide fragments.
• Pharmaceutical Intermediate: A key raw material in the synthesis of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for drug delivery systems.
• Research & Development: Employed in academic and industrial labs for exploring new peptide structures and functions.
• Production of Protected Amino Acids: Acts as a precursor for generating other Boc-protected amino acid active esters.

Basic Information

Product Name	Boc-Met-Onp
CAS No.	2488-18-8
Molecular Formula	C₁₇H₂₄N₂O₆S
Molecular Weight	384.45 g/mol
Synonyms	Boc-Methionine p-Nitrophenyl Ester; N-(tert-Butoxycarbonyl)-L-methionine 4-nitrophenyl ester; (S)-2-((tert-Butoxycarbonyl)amino)-4-(methylthio)butanoic acid 4-nitrophenyl ester; Boc-L-Met-ONp; Boc-L-Methionine ONp ester; Boc-Met-ONp; tert-Butoxycarbonylmethionine p-nitrophenyl ester; N-Boc-L-methionine p-nitrophenyl ester
EINECS	Contact for details

Quality Control

Our Boc-Met-Onp is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation [α]²⁰D	-20.0° to -24.0° (c=1 in DMF)
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.