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N2-[(Benzyloxy)Carbonyl]-L-Asparagine 2,4,5-Trichlorophenyl Ester CAS NO 2480-44-6


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CAS No.:2480-44-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N2-[(Benzyloxy)Carbonyl]-L-Asparagine 2,4,5-Trichlorophenyl Ester is a protected amino acid derivative widely used as a key synthetic intermediate in peptide chemistry. This compound is critical for researchers and manufacturers requiring high-purity building blocks to ensure the fidelity and yield of complex peptide sequences. It is primarily utilized by the pharmaceutical, biotechnology, and advanced research sectors for the development of novel therapeutic peptides and biochemical probes.

Application

  • Peptide Synthesis: Serves as a crucial protected asparagine residue in solid-phase and solution-phase peptide synthesis (SPPS).
  • Pharmaceutical Intermediates: Used in the research and production of active pharmaceutical ingredients (APIs) for peptide-based drugs.
  • Bioconjugation: Acts as a specialized reagent for the site-specific modification of proteins and other biomolecules.
  • Chemical Biology Research: Employed in the synthesis of peptide mimetics, enzyme substrates, and inhibitors for biochemical studies.
  • Custom Oligopeptide Production: A fundamental component for CROs and CDMOs manufacturing custom peptides for clients.

Basic Information

Product Name N2-[(Benzyloxy)Carbonyl]-L-Asparagine 2,4,5-Trichlorophenyl Ester
CAS No. 2480-44-6
Molecular Formula C18H15Cl3N2O5
Molecular Weight 445.68 g/mol
Synonyms Z-Asn-OTcp; Z-L-Asparagine 2,4,5-Trichlorophenyl Ester; N-Cbz-L-Asparagine 2,4,5-Trichlorophenyl Ester; Nα-Carbobenzoxy-L-asparagine 2,4,5-trichlorophenyl ester; (2S)-4-Amino-2-[[(benzyloxy)carbonyl]amino]-4-oxobutyl 2,4,5-trichlorophenyl carbonate; L-Asparagine, N-[(phenylmethoxy)carbonyl]-, 2,4,5-trichlorophenyl ester; CBZ-ASN-OTCP
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Quality Control

Our N2-[(Benzyloxy)Carbonyl]-L-Asparagine 2,4,5-Trichlorophenyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency for sensitive synthetic applications. We provide comprehensive analytical data, including HPLC purity, chiral purity, and identity confirmation. Certificates of Analysis (COA) are available for every batch and can be tailored to meet specific customer requirements or compendial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere to maintain optimal stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% (L-Isomer)
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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