Description

Hyoscyamine Sulfate CAS NO 2472-17-5 is a high-purity pharmaceutical-grade anticholinergic alkaloid salt derived from plants of the Solanaceae family. This compound is a critical active pharmaceutical ingredient (API) valued for its precise action on the parasympathetic nervous system. It is primarily required by pharmaceutical manufacturers and research institutions for the formulation of antispasmodic and antisecretory medications.

Application

• Pharmaceutical API: Core ingredient in prescription drugs for treating gastrointestinal disorders, including irritable bowel syndrome (IBS) and peptic ulcers.
• Antispasmodic Formulations: Used in medications to relieve smooth muscle spasms in the bladder, intestines, and biliary tract.
• Pre-Anesthetic Medication: Employed to reduce salivary and bronchial secretions before surgery.
• Ophthalmic Solutions: Component in eye drops used for cycloplegia and mydriasis during diagnostic procedures.
• Analgesic Adjunct: Incorporated into certain pain relief formulations to manage visceral pain.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological and biochemical research.
• Veterinary Medicine: Used in veterinary pharmaceuticals for similar anticholinergic applications in animals.

Basic Information

Product Name	Hyoscyamine Sulfate
CAS No.	2472-17-5
Molecular Formula	C34H48N2O10S
Molecular Weight	676.82 g/mol
Synonyms	Atropine sulfate (isomer); (S)-Hyoscyamine sulfate; Daturine sulfate; Duboisine sulfate; 3α-Tropanyl (S)-tropate sulfate; Tropine tropate sulfate; Levohyoscyamine sulfate; [7(S)-(1α,2β,4β,5α,7β)]-α-(Hydroxymethyl)benzeneacetic acid 9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester sulfate (2:1)
EINECS	219-598-7

Quality Control

Our Hyoscyamine Sulfate is manufactured under strict quality systems to meet the rigorous standards of the pharmaceutical industry. Each batch is tested to ensure compliance with relevant pharmacopoeial monographs, including USP-NF and EP specifications. Comprehensive testing covers identity, purity, assay, and specific impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (TLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Specific Rotation	-24° to -28° (c = 5 in H2O)
Loss on Drying	≤ 1.0%
Sulfated Ash	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.