Description

(25R)-5β-Spirostane-2β,3α-Diol CAS NO 2460-96-0 is a high-purity, steroidal sapogenin derivative characterized by its specific stereochemistry at the 2, 3, and 25 positions. This compound serves as a critical chiral building block and reference standard in advanced pharmaceutical research and synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of steroid-based therapeutics and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the semi-synthesis of steroidal drugs and hormones.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of steroidal compounds.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and receptor binding assays.
• Academic Research: Serves as a starting material for the synthesis of novel steroidal analogs with potential biological activity.
• Natural Product Chemistry: Used as a standard for the identification and quantification of related sapogenins in plant extracts.

Basic Information

Product Name	(25R)-5β-Spirostane-2β,3α-Diol
CAS No.	2460-96-0
Molecular Formula	C27H44O4
Molecular Weight	432.64 g/mol
Synonyms	(25R)-2β,3α-Dihydroxy-5β-spirostan; 2β,3α-Dihydroxyspirostan-5β-ol; Tigogenin-2β,3α-diol; (25R)-Spirostane-2β,3α-diol; 5β-Spirostane-2β,3α-diol, (25R)-; Tigogenin diol
EINECS	Contact for details

Quality Control

Our (25R)-5β-Spirostane-2β,3α-Diol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.