Description

1-Methylestra-1,3,5(10)-Triene-3,17β-Diol 17-Acetate is a synthetic steroid derivative with a specific methyl substitution and acetylated 17-hydroxy group. This compound is of significant interest in pharmaceutical research and development, particularly as a key intermediate or reference standard for novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis and study of steroidal compounds for potential hormonal or anti-inflammatory applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used as a reference standard or starting material in academic and industrial laboratories for studying structure-activity relationships (SAR) of steroid hormones.
• Biochemical Research: Employed in assays and studies investigating steroid receptor binding affinity, metabolism, and enzymatic interactions.
• Process Development: Acts as a model compound for developing and optimizing chemical synthesis and purification processes in a GMP environment.

Basic Information

Product Name	1-Methylestra-1,3,5(10)-Triene-3,17β-Diol 17-Acetate
CAS No.	2456-11-3
Molecular Formula	C21H28O3
Molecular Weight	328.45 g/mol
Synonyms	1-Methylestradiol 17-Acetate; 17β-Acetoxy-1-methylestra-1,3,5(10)-trien-3-ol; 1-Methyl-3,17β-dihydroxyestra-1,3,5(10)-triene 17-acetate; 1-Methylestra-1,3,5(10)-triene-3,17β-diol diacetate (common misnomer); 1-ME2 17-Acetate; 1-Methyl-17β-acetoxyestra-1,3,5(10)-trien-3-ol; 3-Hydroxy-1-methylestra-1,3,5(10)-trien-17β-yl acetate
EINECS	Contact for details

Quality Control

Our 1-Methylestra-1,3,5(10)-Triene-3,17β-Diol 17-Acetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.