Description

Sulfadoxine is a long-acting sulfonamide antibiotic belonging to the chemical class of sulfanilamides. Its primary value lies in its synergistic use with pyrimethamine for the treatment and prevention of specific parasitic infections, offering a potent therapeutic combination. This compound is essential for manufacturers in the pharmaceutical industry, particularly those producing antimalarial medications and veterinary antiprotozoal agents. Its high purity and consistent quality are critical for ensuring the efficacy and safety of the final drug formulations.

Application

• Active Pharmaceutical Ingredient (API) in fixed-dose combination antimalarial drugs (e.g., with Pyrimethamine).
• Key intermediate in the synthesis of specialized sulfonamide-based pharmaceutical compounds.
• Veterinary pharmaceutical applications for the treatment of coccidiosis and other protozoal infections.
• Research and development of new antimicrobial and antiparasitic agents.
• Reference standard in analytical laboratories for quality control and method validation.
• Manufacturing of bulk pharmaceutical products for global health programs.

Basic Information

Product Name	Sulfadoxine
CAS No.	2447-57-6
Molecular Formula	C12H14N4O4S
Molecular Weight	310.33 g/mol
Synonyms	4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide; Sulforthomidine; Fanasil; Sulfadoxin; Sulformethoxine; SDX; N1-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide; Sulphadoxine
EINECS	219-498-8

Quality Control

Our Sulfadoxine is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles, utilizing advanced analytical techniques like HPLC. A Certificate of Analysis (COA) is provided with every shipment, detailing all test results. We can supply material compliant with various pharmacopoeial standards, including USP and EP, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.