Description

(2Alpha,5Alpha,17Beta)-2,17-Dimethylspiro[Androstane-3,3'-[3H]Diazirin]-17-Ol CAS NO 2398-55-2 is a specialized, high-purity steroid derivative featuring a diazirine photoaffinity label. This compound is of significant value as a critical biochemical tool for advanced research in molecular biology and pharmacology. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in receptor mapping, protein-ligand interaction studies, and photolabeling applications.

Application

• Photoaffinity Labeling: Acts as a covalent cross-linking agent to study steroid hormone receptor binding sites and protein interactions.
• Biochemical Research: Used as a molecular probe for investigating the structure and function of androgen and steroid receptors.
• Drug Discovery: Serves as a key intermediate or tool compound in the development and screening of novel therapeutic agents targeting hormonal pathways.
• Metabolic Studies: Employed in tracer studies to elucidate metabolic pathways and biotransformation of steroid analogs.
• Proteomics: Utilized for the identification and characterization of unknown protein targets that bind steroid-like molecules.
• Material Science Research: Potential use in the synthesis of advanced materials with specific molecular recognition properties.

Basic Information

Product Name	(2Alpha,5Alpha,17Beta)-2,17-Dimethylspiro[Androstane-3,3'-[3H]Diazirin]-17-Ol
CAS No.	2398-55-2
Molecular Formula	C₂₁H₃₂N₂O
Molecular Weight	328.50 g/mol
Synonyms	2,17-Dimethylspiro[androstane-3,3'-[3H]diazirin]-17-ol; 17β-Hydroxy-2,17-dimethyl-5α-androstane-3-spiro-3'-[3H]diazirine; Diazirine-labeled steroid; Photoactivatable androgen analog; Spiro[diazirin-3,3'-androstan]-17-ol derivative; [3H]Diazirinyl steroid probe; Androstane-diazirine conjugate
EINECS	Contact for details

Quality Control

Our (2Alpha,5Alpha,17Beta)-2,17-Dimethylspiro[Androstane-3,3'-[3H]Diazirin]-17-Ol is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing purity, specific activity (for radiolabeled versions), and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is strictly light-sensitive and must be handled under subdued light or in amber glass vials to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.