Description

Isonipecotic Acid, 1-Allyl-4-Phenyl-, Ethyl Ester is a versatile and high-purity chemical intermediate of significant importance in advanced organic synthesis. Its unique molecular structure, featuring both an allyl and a phenyl substituent on the piperidine ring, makes it a valuable building block for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents and fine chemical products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Serves as a core scaffold for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex organic molecules for agrochemicals, dyes, and specialty materials.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands or organocatalysts due to its modifiable nitrogen center and stereogenic potential.
• Academic Research: Utilized in universities and R&D labs for methodological studies in heterocyclic and alkaloid chemistry.

Basic Information

Product Name	Isonipecotic Acid, 1-Allyl-4-Phenyl-, Ethyl Ester
CAS No.	2372-70-5
Molecular Formula	C16H21NO2
Molecular Weight	259.34 g/mol
Synonyms	Ethyl 1-Allyl-4-phenylisonipecotate; 1-Allyl-4-phenylpiperidine-4-carboxylic acid ethyl ester; 4-Phenyl-1-(2-propenyl)-4-piperidinecarboxylic acid ethyl ester; 1-Allyl-4-phenyl-4-piperidinecarboxylic acid ethyl ester; Ethyl 1-allyl-4-phenyl-4-piperidinecarboxylate; 4-Carbethoxy-1-allyl-4-phenylpiperidine; NSC 102022
EINECS	Contact for details

Quality Control

Our Isonipecotic Acid, 1-Allyl-4-Phenyl-, Ethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and rigorous in-process controls guarantees a reliable supply of high-grade material for your sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.