Description

Thiazinamium is a quaternary ammonium compound with significant pharmacological activity, primarily recognized for its potent antihistaminic and anticholinergic properties. This makes it a valuable intermediate in the synthesis of advanced pharmaceutical agents targeting allergic and respiratory conditions. It is essential for research and development laboratories, as well as production facilities, in the pharmaceutical and fine chemical industries seeking to develop new therapeutic entities or generic formulations. Thiazinamium CAS NO 2338-21-8 represents a critical building block for innovators focused on neuropharmacology and autonomic nervous system modulation.

Application

• Key synthetic intermediate in the production of antihistamine pharmaceuticals.
• Research chemical for studying histamine H1-receptor antagonists and their mechanisms of action.
• Precursor in the development of compounds with anticholinergic (antimuscarinic) activity.
• Building block for novel chemical entities targeting allergic rhinitis, asthma, and motion sickness.
• Reference standard in analytical laboratories for quality control and method development.
• Intermediate for fine chemical synthesis in contract research and manufacturing organizations (CRMOs).

Basic Information

Product Name	Thiazinamium
CAS No.	2338-21-8
Molecular Formula	C19H24N2S
Molecular Weight	312.47 g/mol
Synonyms	Thiazinamium Methylsulfate; 10-[(1-Methyl-2-pyrrolidinyl)methyl]phenothiazine Methosulfate; N-Methylpyrrolidin-2-ylmethylphenothiazin-10-yl Ammonium Methyl Sulfate; 2338-21-8; Phenothiazine, 10-[(1-methyl-2-pyrrolidinyl)methyl]-, methosulfate; Methosulfate de thiazinamium; Thiazinamium metilsolfato
EINECS	Contact for details

Quality Control

Our Thiazinamium is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of specified impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support cGMP standards for pharmaceutical intermediate applications, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.