Description

(Z)-1,4-Bis(Mesyloxy)-2-Butene CAS NO 2303-47-1 is a high-purity, versatile chemical intermediate characterized by its reactive mesylate (methanesulfonate) groups and defined stereochemistry. This compound matters for its role as a key building block in sophisticated organic synthesis, enabling the controlled introduction of functional groups and the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as cross-coupling reactions, nucleophilic substitutions, and the synthesis of specialized polymers or liquid crystals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in creating molecules with specific stereochemical configurations.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring precise chemical linkages.
• Cross-Coupling Reactions: Serves as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and liquid crystalline materials.
• Nucleophilic Substitution: The mesylate groups are excellent leaving groups, facilitating efficient nucleophilic substitution reactions with amines, thiols, and alkoxides.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing complex organic molecules and exploring new synthetic methodologies.

Basic Information

Product Name	(Z)-1,4-Bis(Mesyloxy)-2-Butene
CAS No.	2303-47-1
Molecular Formula	C6H12O6S2
Molecular Weight	244.28 g/mol
Synonyms	1,4-Dimethanesulfonyloxy-2-butene (Z-isomer); (Z)-1,4-Bis(methanesulfonyloxy)-2-butene; (Z)-2-Butene-1,4-diyl dimethanesulfonate; (Z)-But-2-ene-1,4-diyl bis(methanesulfonate); (Z)-1,4-Dimesyloxy-2-butene; (Z)-1,4-Di-O-methanesulfonyl-2-butene; (2Z)-1,4-Bis(methylsulfonyloxy)but-2-ene
EINECS	Contact for details

Quality Control

Our (Z)-1,4-Bis(Mesyloxy)-2-Butene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity, correct stereochemistry, and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
(Z)-Isomer Content	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.