Description

2-(Trifluoromethyl)Phenyl Isocyanate is a specialized aromatic isocyanate monomer featuring a reactive isocyanate group and a trifluoromethyl substituent on the benzene ring. This compound is valued for its ability to introduce both the phenyl isocyanate moiety and fluorine-containing groups into target molecules, enhancing properties like chemical resistance, thermal stability, and lipophilicity. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing ureas, carbamates, and other functional derivatives.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic structures to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in creating herbicides, fungicides, and insecticides where the trifluoromethyl group can improve biological activity and environmental persistence.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the production of specialty polyurethanes, coatings, and adhesives with enhanced solvent and chemical resistance.
• Liquid Crystal & OLED Materials: Incorporated into the molecular structure of advanced electronic materials to influence dielectric constants and alignment properties.
• Chemical Research & Development: A versatile reagent for constructing diverse heterocycles and functional molecules in medicinal and synthetic chemistry programs.

Basic Information

Product Name	2-(Trifluoromethyl)Phenyl Isocyanate
CAS No.	2285-12-3
Molecular Formula	C8H4F3NO
Molecular Weight	187.12 g/mol
Synonyms	2-Trifluoromethylphenyl isocyanate; α,α,α-Trifluoro-o-tolyl isocyanate; Isocyanic acid, 2-(trifluoromethyl)phenyl ester; 2-(Trifluoromethyl)benzenisocyanate; o-Trifluoromethylphenyl isocyanate; 1-Isocyanato-2-(trifluoromethyl)benzene; 2-Tolyl isocyanate, α,α,α-trifluoro-
EINECS	218-927-0

Quality Control

Our 2-(Trifluoromethyl)Phenyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay by GC/HPLC and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, containers must be kept sealed under a dry inert atmosphere (e.g., nitrogen) to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.