Description

8-tert-Butyl-1,4-Dioxaspiro[4.5]Decane is a specialized spirocyclic acetal compound, serving as a crucial intermediate and building block in advanced organic synthesis. Its unique sterically hindered structure makes it valuable for creating complex molecules with specific conformational properties. This chemical is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fragrance sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex drug candidates, particularly those requiring rigid, spirocyclic frameworks to modulate biological activity and pharmacokinetics.
• Agrochemical Synthesis: Serves as a key precursor for developing novel pesticides and herbicides, where the tert-butyl and spirocyclic groups can enhance stability and efficacy.
• Fragrance and Flavor Chemistry: Acts as a building block for synthesizing unique musk-like or woody odorants due to its volatile and structurally constrained nature.
• Material Science Research: Employed in the development of specialty polymers, ligands for catalysis, and other advanced organic materials.
• Organic Synthesis Reagent: Utilized as a protected form of a ketone or as a sterically hindered substrate in various name reactions and methodological studies.

Basic Information

Product Name	8-tert-Butyl-1,4-Dioxaspiro[4.5]Decane
CAS No.	2223-71-4
Molecular Formula	C12H22O2
Molecular Weight	198.30 g/mol
Synonyms	8-tert-Butyl-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decane, 8-(1,1-dimethylethyl)-; 8-(tert-Butyl)-1,4-dioxaspiro[4.5]decane; 8-tert-Butyl-1,4-dioxaspiro[4,5]decane; 8-(1,1-Dimethylethyl)-1,4-dioxaspiro[4.5]decane; Spirocyclic acetal of 4-tert-butylcyclohexanone; 4-tert-Butylcyclohexanone ethylene ketal
EINECS	Contact for details

Quality Control

Our 8-tert-Butyl-1,4-Dioxaspiro[4.5]Decane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.