Description

4-Trimethylsilylbenzaldehyde is a versatile organosilicon compound featuring a reactive aldehyde group protected by a trimethylsilyl moiety. This unique structure makes it a valuable building block in organic synthesis, particularly for introducing silicon-protected benzaldehyde units into complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for the development of novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring silicon-containing or protected aldehyde functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the silyl group aids in stability and reactivity control during synthesis.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of silicon-based organic semiconductors, liquid crystal displays (LCDs), and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions, such as Suzuki and Heck reactions, for constructing biaryl systems.
• Organic Synthesis Reagent: Employed as a protecting group for aldehydes and as a versatile electrophile in nucleophilic addition and Grignard reactions.
• Polymer & Resin Modification: Used to introduce aromatic aldehyde groups into polymer chains for specialty resins and advanced polymeric materials.

Basic Information

Product Name	4-Trimethylsilylbenzaldehyde
CAS No.	2199-32-8
Molecular Formula	C10H14OSi
Molecular Weight	178.30 g/mol
Synonyms	p-(Trimethylsilyl)benzaldehyde; (4-Formylphenyl)trimethylsilane; 4-(Trimethylsilyl)benzaldehyde; Benzaldehyde, 4-(trimethylsilyl)-; Trimethyl(4-formylphenyl)silane; p-Trimethylsilylbenzaldehyde; 4-TMS-benzaldehyde
EINECS	218-599-7

Quality Control

Our 4-Trimethylsilylbenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.