Description

4-Methyl Hydrogen L-Aspartate is a specialized derivative of the amino acid L-aspartic acid, featuring a methyl group substitution. This modification imparts unique steric and electronic properties, making it a valuable chiral building block and intermediate in sophisticated organic synthesis. It is particularly sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors. The compound is supplied to global markets with a focus on high purity and batch-to-batch consistency.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in neurological and metabolic drug candidates.
• Peptide Synthesis: Used in the preparation of modified peptides and peptidomimetics, where the methyl group can influence conformation and biological activity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate the function of aspartate-specific enzymes and receptors.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material for the asymmetric synthesis of complex natural products and other non-racemic compounds.
• Flavor & Fragrance Precursor: Acts as a potential intermediate in the synthesis of certain flavor enhancers and aroma chemicals.
• Cosmetic Ingredient Synthesis: Used in the development of specialized amino acid derivatives for advanced skincare formulations.

Basic Information

Product Name	4-Methyl Hydrogen L-Aspartate
CAS No.	2177-62-0
Molecular Formula	C5H9NO4
Molecular Weight	147.13 g/mol
Synonyms	L-4-Methylaspartic Acid; (2S)-2-Amino-2-methylbutanedioic Acid; (S)-2-Amino-2-methylsuccinic Acid; 4-Methyl-L-aspartic Acid; 4-Methylaspartate; H-4-Me-Asp-OH; 2-Amino-2-methylbutanedioic Acid, (S)-; 4-Methyl-DL-aspartic Acid (related)
EINECS	218-548-1

Quality Control

Our 4-Methyl Hydrogen L-Aspartate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and specific impurity profiles. We adhere to cGMP principles where applicable to guarantee reliable supply and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.