Description

L-Leucine Ethyl Ester Hydrochloride is a protected amino acid derivative essential for advanced peptide synthesis and pharmaceutical research. This high-purity building block provides a crucial handle for introducing the hydrophobic L-leucine side chain under controlled conditions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic peptides and bioactive compounds.

Application

• Pharmaceutical Intermediates: A key chiral building block in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Biochemical Research: Used in the study of enzyme-substrate interactions, protein folding, and as a precursor for custom amino acid analogs.
• Fine Chemical Synthesis: Serves as an intermediate in the production of specialized surfactants, ionic liquids, and chiral catalysts.
• Cosmetic Peptides: Employed in the synthesis of bioactive peptides for advanced skincare and anti-aging formulations.
• Agrochemical Development: Utilized in creating novel, bioactive peptide-based crop protection agents.

Basic Information

Product Name	L-Leucine Ethyl Ester Hydrochloride
CAS No.	2143-40-0
Molecular Formula	C8H18ClNO2
Molecular Weight	195.69 g/mol
Synonyms	L-Leucine ethyl ester HCl; Ethyl L-leucinate hydrochloride; H-Leu-OEt·HCl; (S)-2-Amino-4-methylpentanoic acid ethyl ester hydrochloride; Leucine ethyl ester monohydrochloride; L-2-Amino-4-methylvaleric acid ethyl ester hydrochloride; L-Leucine, ethyl ester, hydrochloride (1:1); L-Leucine ethylester hydrochloride
EINECS	218-401-9

Quality Control

Our L-Leucine Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch is tested to ensure high chemical purity, correct stereochemistry, and compliance with relevant standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.