Description

Cyproterone is a synthetic steroidal antiandrogen with potent progestogenic activity, widely recognized for its critical role in endocrine therapy. Its primary value lies in its ability to competitively block androgen receptors, making it a cornerstone in managing conditions driven by androgens. This compound is essential for pharmaceutical manufacturers and research institutions developing treatments for hormone-dependent cancers, such as prostate cancer, and other conditions like severe acne and hirsutism.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of antiandrogen medications for the treatment of advanced prostate carcinoma.
• Hormone Therapy: Key component in combination therapies (e.g., with ethinylestradiol) for treating severe androgenization in women, including acne and hirsutism.
• Oncological Research: Used in preclinical and clinical research to study androgen receptor pathways and develop new cancer therapeutics.
• Endocrinology: Employed in studies of hormonal feedback mechanisms and the development of novel endocrine-disrupting agent models.
• Dermatology: Serves as a reference standard in the development of topical or systemic treatments for severe, hormone-influenced skin disorders.
• Veterinary Medicine: Applied in the management of hormonal disorders and certain reproductive conditions in animals.

Basic Information

Product Name	Cyproterone
CAS No.	2098-66-0
Molecular Formula	C22H27ClO3
Molecular Weight	374.90 g/mol
Synonyms	Cyproterone Acetate (common salt form); 6-Chloro-17α-hydroxy-1α,2α-methylenepregna-4,6-diene-3,20-dione; SH-80881; Androcur; Cyprone; 1,2α-Methylene-6-chloro-δ6-17α-acetoxyprogesterone; NSC-81430
EINECS	218-248-5

Quality Control

Our Cyproterone is manufactured under strict quality management systems, targeting high-purity standards suitable for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including HPLC for assay and impurity profiling, to ensure identity, potency, and purity. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing compliance with agreed specifications. Our quality commitment aligns with cGMP principles to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.