Description

1,2-Benzenedicarboxylic Acid Bis(Trimethylsilyl) Ester is a versatile organosilicon derivative of phthalic acid, serving as a key protected intermediate and silylating agent in advanced organic synthesis. This compound is valued for its ability to introduce the trimethylsilyl (TMS) group, which can protect reactive functional groups, modify solubility, or act as a precursor in the production of specialty silicones and polymers. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used as a protected form of phthalic acid or as a silylating agent in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and plant growth regulators where silicon incorporation is beneficial.
• Polymer & Material Science: Acts as a monomer or modifying agent in the synthesis of silicon-containing polyesters, polyimides, and other high-performance polymers.
• Organic Synthesis Reagent: Functions as a versatile silylating agent to protect hydroxyl or carboxyl groups, facilitating complex reaction sequences.
• Cross-Coupling Reactions: May serve as a reagent in palladium-catalyzed or other metal-mediated coupling reactions to form carbon-silicon bonds.
• Analytical Chemistry: Used to derivative polar compounds for Gas Chromatography (GC) or Mass Spectrometry (MS) analysis to improve volatility and detection.

Basic Information

Product Name	1,2-Benzenedicarboxylic Acid Bis(Trimethylsilyl) Ester
CAS No.	2078-22-0
Molecular Formula	C14H22O4Si2
Molecular Weight	310.50 g/mol
Synonyms	Bis(trimethylsilyl) phthalate; Phthalic Acid Bis(trimethylsilyl) Ester; 1,2-Bis(trimethylsiloxycarbonyl)benzene; Trimethylsilyl phthalate; TMS-phthalate; Phthalic Acid Di(trimethylsilyl) Ester; DMTSP (Dimethyl Trimethylsilyl Phthalate - common abbreviation); O,O'-Bis(trimethylsilyl) phthalate
EINECS	218-194-7

Quality Control

Our production of 1,2-Benzenedicarboxylic Acid Bis(Trimethylsilyl) Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting cGMP and ISO 9001 quality management principles for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC or HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.