Description

Phenylacetoxytrimethylsilane is a versatile organosilicon reagent featuring a reactive silyl ester group. This compound is valued for its role as a key intermediate and protecting group in sophisticated organic synthesis, particularly in the pharmaceutical and fine chemical sectors. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), advanced materials, and specialty agrochemicals who require reliable, high-purity building blocks.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Silicon-Based Protecting Group: Used in multi-step organic synthesis to temporarily protect carboxylic acid functionalities under specific reaction conditions.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, fragrances, and advanced material precursors.
• Agrochemical Research: Serves as an intermediate in the development of novel pesticides and herbicides.
• Material Science: Used in the surface modification of materials and the synthesis of silicon-containing polymers.
• Laboratory Reagent: A valuable reagent for academic and industrial R&D in synthetic organic chemistry.

Basic Information

Product Name	Phenylacetoxytrimethylsilane
CAS No.	2078-18-4
Molecular Formula	C11H16O2Si
Molecular Weight	208.33 g/mol
Synonyms	Trimethylsilyl phenylacetate; Phenylacetic acid trimethylsilyl ester; (Trimethylsilyloxy)(phenyl)acetaldehyde (tautomer); Acetic acid, phenyl-, trimethylsilyl ester; TMSPA; Phenylacetic Acid TMS Ester; α-(Trimethylsiloxy)benzeneacetonitrile (related nitrile); Trimethyl(phenylacetoxy)silane
EINECS	218-203-3

Quality Control

Our Phenylacetoxytrimethylsilane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (IR, NMR), to ensure high chemical purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.