Description

3,4-Dimethoxybenzoic Acid Trimethylsilyl Ester is a versatile organosilicon-protected derivative of veratric acid, serving as a crucial synthetic intermediate and protecting group reagent. Its primary value lies in enabling complex organic synthesis by providing a stable, silylated carboxylate group that is resistant to many reaction conditions but can be selectively deprotected. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable building blocks for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those requiring protected carboxylic acid functionalities during multi-step sequences.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and plant growth regulators that incorporate dimethoxyphenyl motifs.
• Organic Synthesis Reagent: Acts as a trimethylsilyl (TMS) ester protecting group for carboxylic acids, facilitating reactions on other parts of the molecule.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced organic electronic materials and liquid crystal compounds.
• Flavor & Fragrance Chemistry: Intermediate in the production of sophisticated aroma chemicals and flavoring agents with veratrole-related structures.
• Polymer Modification: Used to introduce functional, silylated benzoic acid groups into polymer chains for specialty material applications.
• Analytical Reference Standard: Employed as a high-purity standard in chromatographic analysis (GC, HPLC) for method development and quality control.

Basic Information

Item	Details
Product Name	3,4-Dimethoxybenzoic Acid Trimethylsilyl Ester
CAS No.	2078-16-2
Molecular Formula	C₁₂H₁₈O₄Si
Molecular Weight	254.35 g/mol
Synonyms	Veratric Acid Trimethylsilyl Ester; Trimethylsilyl 3,4-Dimethoxybenzoate; 3,4-Dimethoxybenzoic Acid TMS Ester; TMS Veratrate; (3,4-Dimethoxyphenyl)carboxylic Acid Trimethylsilyl Ester; Benzoic Acid, 3,4-dimethoxy-, trimethylsilyl ester; Trimethylsilyl 3,4-dimethoxybenzoate
EINECS	Contact for details

Quality Control

Our production of 3,4-Dimethoxybenzoic Acid Trimethylsilyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical B2B applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and GC-MS for identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality system is designed to support customer needs in regulated environments, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere (e.g., nitrogen) for long-term preservation of quality. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.