Description

Benzoic Acid, 3-Methoxy-4-[(Trimethylsilyl)Oxy]-, Trimethylsilyl Ester is a specialized organosilicon derivative of a substituted benzoic acid, featuring dual trimethylsilyl (TMS) protecting groups. This compound is valued for its role as a key synthetic intermediate and protecting group reagent in advanced organic synthesis, particularly for sensitive phenolic and carboxylic acid functionalities. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Serves as a protected synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Advanced Material Precursor: Acts as a building block for creating specialized monomers, ligands, or functionalized polymers in material science.
• Organic Synthesis Reagent: Employed as a versatile protecting group agent for phenolic hydroxyl and carboxylic acid groups under mild conditions.
• Chemical Research: Essential for academic and industrial R&D in methodology development and exploring new chemical entities.
• Fine Chemical Production: Utilized in the custom synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	Benzoic Acid, 3-Methoxy-4-[(Trimethylsilyl)Oxy]-, Trimethylsilyl Ester
CAS No.	2078-15-1
Molecular Formula	C14H24O4Si2
Molecular Weight	312.51 g/mol
Synonyms	3-Methoxy-4-(trimethylsilyloxy)benzoic Acid Trimethylsilyl Ester; Vanillic Acid Bis(trimethylsilyl) Ether; 4-Hydroxy-3-methoxybenzoic Acid Bis(trimethylsilyl) Ester; Bis(trimethylsilyl) Vanillate; TMS Vanillate; Vanillic Acid Bis-TMS Ester; 3-Methoxy-4-(trimethylsiloxy)benzoic Acid Trimethylsilyl Ester; Bis-O-trimethylsilyl Vanillic Acid
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 3-Methoxy-4-[(Trimethylsilyl)Oxy]-, Trimethylsilyl Ester is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance in research and cGMP-aligned development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.