Description

4-Methoxybenzoic Acid Trimethylsilyl Ester is a versatile organosilicon derivative of 4-methoxybenzoic acid, valued for its role as a protected intermediate in advanced organic synthesis. Its primary commercial significance lies in enabling efficient, high-purity reactions, particularly in the production of complex molecules where precise functional group manipulation is critical. This compound is essential for R&D and manufacturing within the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a key building block for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of drug candidates, particularly those containing substituted benzoic acid moieties.
• Agrochemical Synthesis: Used in the development and production of advanced herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for mesogenic units and electron-transport materials in display and lighting technologies.
• Polymer & Resin Modifier: Employed to introduce methoxybenzoate functional groups into polymer chains to alter thermal and solubility properties.
• Flavor & Fragrance Ingredient Synthesis: Acts as an intermediate in the creation of complex aromatic esters used in high-value perfumery and flavoring agents.
• Analytical Chemistry Standard: Utilized as a reference standard or derivatization agent in chromatographic analysis (GC, GC-MS) for compound identification and quantification.
• Organic Synthesis Reagent: Facilitates various reactions, including silylation for protection/deprotection strategies and cross-coupling reactions.

Basic Information

Product Name	4-Methoxybenzoic Acid Trimethylsilyl Ester
CAS No.	2078-14-0
Molecular Formula	C11H16O3Si
Molecular Weight	224.33 g/mol
Synonyms	p-Anisic Acid Trimethylsilyl Ester; Trimethylsilyl 4-Methoxybenzoate; 4-Methoxybenzoic Acid TMS Ester; TMS p-Anisate; (4-Methoxyphenyl)carboxylic Acid Trimethylsilyl Ester; Benzoic Acid, 4-methoxy-, trimethylsilyl ester; Trimethyl(p-methoxybenzoyloxy)silane
EINECS	Contact for details

Quality Control

Our production of 4-Methoxybenzoic Acid Trimethylsilyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment, supporting compliance in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.