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4-[Bis(2-Chloroethyl)Amino]Benzamide CAS NO 2045-42-3


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CAS No.:2045-42-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-[Bis(2-Chloroethyl)Amino]Benzamide is a specialized nitrogen mustard derivative with significant utility in advanced chemical synthesis. This compound matters as a critical building block for researchers and manufacturers developing targeted pharmaceutical agents and other high-value fine chemicals. It is primarily needed by the pharmaceutical, agrochemical, and life science research industries for applications in medicinal chemistry and as a precursor for more complex molecular structures.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of nitrogen mustard-based chemotherapeutic agents and other bioactive molecules.
  • Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of novel targeted therapies.
  • Alkylating Agent Synthesis: Serves as a fundamental starting material for creating specialized alkylating compounds used in various chemical processes.
  • Bioconjugation & Linker Chemistry: Employed in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems due to its reactive chloroethyl groups.
  • Agrochemical Development: Intermediate in the research and production of certain specialized pesticides and herbicides.
  • Biochemical Probe Development: Used to create probes for studying biological mechanisms involving alkylation and DNA interaction.

Basic Information

Product Name 4-[Bis(2-Chloroethyl)Amino]Benzamide
CAS No. 2045-42-3
Molecular Formula C11H14Cl2N2O
Molecular Weight 261.15 g/mol
Synonyms N,N-Bis(2-chloroethyl)-4-aminobenzamide; 4-[Bis(2-chloroethyl)amino]benzoic acid amide; Benzamide, 4-[bis(2-chloroethyl)amino]-; p-[Bis(2-chloroethyl)amino]benzamide; NSC 176319; Chlorambucil Amide; CB-1348 Amide; Leukeran Amide (related derivative)
EINECS Contact for details

Quality Control

Our 4-[Bis(2-Chloroethyl)Amino]Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 1.0%
Related Substances (HPLC) Contact for details
Heavy Metals < 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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